Story: Golmaal Again is yet another fun filled ride about two gangs who are unable to stand each other since their childhood and how they repulse each other even after they grow up. It is yet another hilarious adventure with its fair share of thrills that are sure to surprise the audience and fill their hearts with laughter and joy. It is a film that will surely make everyone laugh, cry and realize the importance of how beautiful life is.
Gopal (Ajay Devgn), Madhav , Lucky , Laxman 1 and Laxman 2 are orphans who stay in an orphanage and are the first batch to have stayed there. The orphanage is funded and managed by Jamnadas(Uday Tikekar), who was a successful businessman, and is located in Ooty.
Gopal is bad-tempered and breaks the fingers of people who show him fingers. At night, Gopal slept with fear that a ghost will come in front of him, which led to his friendship with Laxman 1. Among the orphans, Jamnadas’s favourite was Pappi who tends to forget things. One night, Gopal, Madhav, Lucky and both Laxman find a baby girl at the gate of the orphanage. They name her Khushi. They take care of her till she grows up. The five boys know Anna as she worked in a library with her father where orphans used to frequently visit. Anna could see spirits and the five boys knew about this.
One day while playing cricket, the ball goes to a vacant bungalow belonging to Jamnadas’s close friend. Madhav scared Gopal which led to a fight. Gopal gets punished and hence decided to leave the orphanage with Laxman 1. Madhav, Lucky and Laxman 2 also left. Jamnadas and Khushi missed them every day. Later, Khushi was adopted by colonel. Gopal and Laxman 1 work for Babli Bhai (Sanjay Mishra). Madhav, Laxman 2 and Lucky work for Vasooli Bhai (Mukesh Tiwari). These trio work to fear people and make them leave the house. The five find out that Jamnadas has died and there is a ritual to be done for him. They return to the orphanage after 25 years. They find paintings on the walls of the orphanage.
The gang encounters with some spiritual bodies and finds out the truth about the Jamnadas Orphanage where they were brought up.